Requisition #: A-73782-11
Status: Full Time
School: School of Medicine
Department/Program: Wilmer Ophthalmological Institute
Location City: Baltimore
Location State: MD
Location Zip Code: 21287
Closing Date: Open until filled
To apply: apply.interfolio.com/73782
A Postdoctoral Research Fellowship position is available in the Optic Nerve Regeneration and Neuroprotection Laboratory at the the Wilmer Eye Institute. We are seeking a highly qualified, motivated, and creative scientist with expertise in cellular neuroscience and/or molecular biology. Our laboratory is a founding member of the cross-disciplinary Hopkins Optic Nerve Regeneration Initiative, and the successful candidate will play a central role in a collaborative project investigating the functional integration of stem cell-derived neurons into the mammalian retina. The laboratory is directed by Thomas Johnson, and project co-mentors for the successful applicant will include ARVO Friedenwald Award winners Harry Quigley and Don Zack.
Retinal ganglion cell (RGC) replacement holds potential for restoring lost vision in optic neuropathies including glaucoma. While worldwide efforts are making strides in promoting RGC axon regeneration from the eye to the brain, whether and how transplanted RGCs integrate with the recipient inner retina remains poorly understood. The successful applicant will lead a project aimed at characterizing and optimizing the functional retinal integration of transplanted stem cell-derived RGCs in multiple rodent models of glaucoma and optic neuropathy. Relevant techniques to be employed include cell and tissue culture, multiphoton and electron microscopy, semi-automated and automated 3D image analysis, CRISPR/Cas9 gene editing, RNA sequencing, and rodent microsurgery.
This is a two-year full-time position, renewable yearly based on successful performance.
- Degree: PhD or equivalent in neuroscience, cell biology, molecular biology, or a closely related field
- Related laboratory experience required
- Skills: Basic knowledge and skills in animal surgery and micro-dissection, histology, multiphoton microscopy, cell biology, and molecular biology are desired. Ideal qualities in the candidate include strong analytical and problem-solving skills, excellent communication and teamwork, and an interest in visual neuroscience.
- A strong publication record is required.
Note: This position requires working with rodents on a frequent basis.
To apply, please submit your CV, brief statement of interest and career goals (1-2 page max), as well as three reference letters. Please apply through the "Apply Now" link.
For questions, please contact the Principle Investigator:
Thomas V Johnson III, MD, PhD
Assistant Professor of Ophthalmology
Wilmer Eye Institute, Johns Hopkins University
600 North Wolfe Street, Maumenee B-110
Baltimore, MD, USA 21287
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